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DOC 2025
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Coleen Murphy, Ph.D.: Why We Need a Reproductive Clock
It’s a question both sensitive and crucial for Coleen Murphy, Ph.D., Princeton University’s Professor of Genomics and Molecular Biology: How long can women have children?
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Dr. Helen M. Blau: The Potential to Reverse Muscle Aging
Stanford’s Dr. Helen Blau found an enzyme blocking muscle repair with age — and a drug that could reverse it, impacting muscle wasting and cartilage…
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Dr. Leonard Zon: Cracking the Code on Mutant Stem Cells
Leonard Zon, M.D., the Grousbeck Professor of Pediatric Medicine at Harvard Medical School spoke about his research on stem cell biology at DOC 2025.
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The Promising Terrain of Stem Cells
Harvard Medical School’s Dr. Leonard Zon and Stanford University’s Dr. Helen M. Blau spoke about the promise of stem cells and longevity at DOC 2025.
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Dr. Eric Verdin: Longevity Patients Are Prescribing Themselves
With longevity medicine, Dr. Eric Verdin, Chief Executive Officer of the Buck Institute for Research on Aging, believes physicians stand at a crossroads.
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Dr. Michael Snyder: Aging Is Not Linear. Neither is Our Health
Our health trajectory does not follow a straight line, says Michael Snyder, Ph.D, the Stanford W. Ascherman Professor in Genetics at Stanford Medicine.
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Dr. Nicole Sirotin: The Case for Longevity Medicine Standards
Institute for Healthier Living Abu Dhabi CEO Dr. Nicole Sirotin, has helped develop a standards-driven approach to longevity medicine for patient care.
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Dr. Claire Clelland: From Genetic Mutations to Targeted Cures
Dr. Claire Clelland, UCSF’s John D French Alzheimer’s Foundation Endowed Chair, believes biologic therapies could reach clinical trials faster by testing them with human tissue.
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DOC 2025 Video: Brain Disease Breakthroughs
Dr. Eric Verdin spoke with Dr. Li Gan, Dr. Claire Clelland, and Dr. David Jones on neurodegenerative disease discoveries and novel therapies at DOC 2025.
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Dr. Li Gan: The Role of Tau and Inflammation in Alzheimer’s Research
Dr. Li Gan of Weill Cornell Medicine is shifting Alzheimer’s research beyond amyloid, focusing on tau protein and inflammation as key drivers of cognitive decline.
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Dr. David Jones: Democratizing Access to Specialized Brain Care
Dr. David Jones, Director of Mayo Clinic’s Neurology Artificial Intelligence Program, developed StateViewer, an AI tool that diagnoses 14 types of dementia using brain scans.
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Dr. Britney Blair: It’s Time to Talk About Sex
To Dr. Britney Blair, Co-Founder and Chief Science Officer of Lover, sex is linked to a decreased risk of anxiety, depression, and even chronic disease.
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Dr. George Slavich: How Ten Minutes of Negativity Can Harm The Body
Teaching people how to develop psychosocial resilience may mitigate acute social pain and reduce stressors to improve overall health, says UCLA’ s Dr. George Slavich.
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Dr. Elissa Epel: The Repairing Power of Rest
UCSF’s Dr. Elissa Epel is well-versed in the effects of chronic stress on the body as expressed through biological aging and other impacts, including depression.
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DOC 2025 Video: The Science of Sex, Stress, and Longevity
Dr. Elissa Epel, Dr. Britney Blair, and Dr. George Slavich say roadmaps for a long, happy life involve sex, stress reduction, and a mindfulness practice.
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Dr. Daisy Robinton: ‘We Need Radical Transformation’
In the women’s health space, Dr. Daisy Robinton’s voice is powerful. After selling her company Oviva Therapeutics, she knows the challenges facing women’s health companies.
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Bailey Renger: Improving Breast Cancer Screening and Specificity
A cancer scare sparked Bailey Renger’s decision to found BeSound, a breast imaging company improving detection for women underserved by today’s screening options.
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Dr. Max Allsworth: Detecting Disease Through Breath Analysis
Chief Science Officer of Owlstone Medical Dr. Max Allsworth is working to uncover hidden signs of disease from cirrhosis to cancer from analyzing one’s breath.
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Roma Van der Walt: Creating Optimal Health and Longevity for Women
When Roma Van der Walt, former professional athlete and founder and CEO of Vitelle talks about women’s bodies and physiology, she speaks from experience.
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Dr. Jennifer Garrison: Untangling the Truth About Female Hormone Therapy
USC and UCSF’s Dr. Jennifer Garrison is a champion of bringing clarity to hormone therapy for women, working with others to dispel myths and misconceptions.
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Dr. Kara Goldman: Why Ovarian Health Matters Beyond Fertility Alone
Northwestern University’s Dr. Kara Goldman, understands that the ovary serves as a vehicle for women’s fertility — and provides insights into female longevity and overall…
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Dr. Kari Nadeau: Tracking Hidden Microplastics in Our Bodies
Dr. Kari Nadeau, Harvard’s Chair of the Department of Environmental Health, believes understanding the effect of the microplastics our body ingests and inhales is critical.
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Dr. Stephen Williams: Blood Proteins Reveal Hidden Health Risks
To Dr. Stephen Williams, Chief Medical Officer of Standard BioTools, proteins and their network of patterns hold clues to the health of our bodies.
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Dr. Heather Hirsch: Building a New Model for Menopause Support
Hormone replacement therapy (HRT) for women in menopause serves as a driver for Dr. Heather Hirsch, founder of science-based concierge clinic, The Collaborative.
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DOC 2025 Video: The Next Generation of Biomarkers
Dr. Stephen Williams, Dr. Max Allsworth, and Dr. Kari Nadeau, talk about the secrets held by the human body foretelling potential illness before symptoms appear.
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DOC 2025 Video: Innovative Women’s Health Startups Face Investment Headwinds
Roma Van der Walt, Bailey Renger, and Dr. Daisy Robinton explored opportunities and challenges facing women’s health, including how technology is shifting women’s health care.
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DOC 2025 Video: How To Fuel Longevity
Helyx Health’s Dr. Tony Masri and USC’s Dr. Valter Longo explored the bedrock of longevity science from protein intake to circadian rhythms.
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Brooks Tingle: John Hancock Has Lessons For All Insurers
John Hancock CEO Brooks Tingle reimagined the life insurance model by spotlighting a powerful alignment: What’s good for customers is also good for business.
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Dr. Tony Masri: The Sleep-Longevity Connection Explained
Neurologist Dr. Tony Masri, co-founder and CEO of Helyx Health, believes the quantity and quality of sleep are, in part, the bedrock of our longevity.
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Dr. Valter Longo: Fasting Your Way to Longevity
Reducing caloric intake for a period of time can help extend longevity and fight disease, says Dr. Valter Longo, the Director of USC’s Longevity Institute.
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DOC 2025 VIDEO: The High-Stakes Gamble of Longevity Medicine: Where Breakthrough Science Meets the Wild West
Dr. Nicole Sirotin, Dr. Eric Verdin and Dr. Jordan Shlain talked about the need to balance progress in cutting-edge longevity research while still protecting patients.
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DOC 2025 Video: The Science of Women’s Health Takes Center Stage, Just Before The FDA Acts
Dr. Kara Goldman, Dr. Heather Hirsch, and Dr. Jennifer Garrison spoke with Dr. Stephanie Kuku about the myth’s and misconception’s surrounding hormone therapy.
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DOC 2025 Video: The Power of Aligned Partners
Researchers, physicians, entrepreneurs, and changemakers united around a shared belief: that collective wisdom cuts through healthcare noise to reveal our true north — science.
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VIDEO: That DOC Magic, 2025 Edition
Our videos highlighting DOC 2025 — a taste of the energy, inspiration and also the community that gathered in Wine Country this fall.
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DOC 2025: Dr. Shlain’s Roundup
We covered ten topics at DOC 2025, and the thread running through them all is this: the future of healthcare isn’t waiting for permission.
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Clinical Breakthroughs | Helen M. Blau, Ph.D. Joins DOC 2025 as a Specialist
The pioneering research of Stanford University biologist Helen Blau, Ph.D. centers on stem cells and aging, providing evidence that human cell fate is reprogrammable.
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Clinical Breakthroughs | Brooks Tingle Joins DOC 2025 as a Specialist
John Hancock’s President and CEO Brooks Tingle believes the life insurance industry has a unique opportunity to help customers live longer, healthier, better lives.
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Clinical Breakthroughs | Leonard Zon, M.D. Joins DOC 2025 as a Specialist
Leonard Zon, M.D., Harvard Medical School’s Grousbeck Professor of Pediatric Medicine, is a stem cell pioneer, transforming therapeutic opportunities to treat and cure diseases.
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Welcome Our 2025 DOC Fellows!
We’re thrilled to announce our DOC 2025 Fellows Class, 19 extraordinary entrepreneurs, doctors and academics joining from around the world in Yountville this year.
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Clinical Breakthroughs and AI | David T. Jones, M.D. Joins DOC 2025 Faculty
David T. Jones, M.D., the Director of the Mayo Clinic Neurology Artificial Intelligence Program, has expanded the therapeutics and clinical care of neurodegenerative disorders.
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AI | Anitha Kannan, Ph.D. Joins DOC 2025 as a Specialist
Anitha Kannan, Ph.D., Vice President of AI at Curai Health, is a researcher and leader in applying artificial intelligence to quality healthcare.
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Clinical Breakthroughs | Heather Hirsch, M.D., M.S., MSCP Joins DOC Faculty
Heather Hirsch, M.D., founder and CEO of The Collaborative, is a perimenopause and menopause expert who advocates for personalized pathways in women’s healthcare.
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Clinical Breakthroughs | John Osborne, M.D. Joins DOC 2025 Faculty
John Osborne, M.D., ClearCardio’s co-founder and CMO, takes an approach to cardiovascular care focused on tracking, treating and preventing heart disease before it strikes.
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Clinical Breakthroughs | Li Gan, Ph.D. Joins DOC 2025 Faculty
Weill Cornell Medicine Neuroscientist Li Gan, Ph.D., is a leading researcher in Alzheimer’s and fundamentally shifting the exploration of treatments for neurodegenerative diseases.
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Clinical Breakthroughs | Nicole Sirotin, M.D. Joins DOC 2025 as a Specialist
Nicole Sirotin, M.D., CEO of the Institute for Healthier Living Abu Dhabi, merges research, clinical care, and technology to advance healthy longevity.
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Valley Legend Reid Hoffman Joins DOC 2025 Debate on “When, if ever, will AI replace doctors?”
Entrepreneur Reid Hoffman — LinkedIn co-founder, Inflection AI, Manas AI, early PayPal executive, and Microsoft Board Director — joins us at DOC 2025.
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Clinical Breakthroughs | Claire Clelland, M.D., Ph.D., M.Phil Joins DOC 2025 Faculty
Neurologist Claire Clelland, M.D., Ph.D., researches neurodegenerative diseases at UCSF, where she holds the John D. French Alzheimer’s Foundation Endowed Chair.
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Women’s Health | Kara Goldman, M.D. Joins Doc 2025 Faculty
Clinician and fertility health pioneer Kara Goldman, M.D. conducts trail-breaking research on reproductive longevity as Director of Fertility Preservation at Northwestern University.
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Women’s Health | Roma van der Walt Joins DOC 2025 as a Specialist
Roma van der Walt, founder and CEO of female healthcare firm Vitelle, is transforming health metrics into longevity solutions tailored to female bodies.
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Women’s Health & AI | Bailey Renger Joins DOC 2025 Faculty
As founder and CEO of the healthcare company BeSound, Bailey Renger is shifting how breast cancer can be detected using AI-assisted ultrasound imaging technology.
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Clinical Breakthroughs | Stephen Williams, M.D., Ph.D. Joins DOC 2025 Faculty
Stephen Williams, Chief Medical Officer of Standard BioTools, oversees Standard BioTools’ SomaScan Platform, a proteomic technology using modified DNA aptamers to bind to specific proteins.
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Clinical Breakthroughs | George Slavich, Ph.D. Joins DOC 2025 Faculty
Founding Director of the Laboratory for Stress Assessment and Research at UCLA, George Slavich investigates how social experiences can affect biological systems and our genome.
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Clinical Breakthroughs | Tony Masri, M.D. Joins DOC 2025 Faculty
Neurologist and board-certified sleep specialist Tony Masri, M.D. has dedicated his research and practice to sleep and its effect on overall health.
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Special Preview: This Year’s Living Room Lab
DOC 2025’s Living Room Lab features cutting edge diagnostics available to DOC participants including OURA, Grail, SimonMed Imaging, Aetas Diagnostics, Jona and more.
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Bridging the Gap with Science Skeptics: A Strategic Approach
Dr. Jordan Shlain suggests that before diving into any defense of science, ask the skeptic, “What’s the most important question you’d like to have answered?”
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Clinical Breakthroughs | Valter Longo, Ph.D. Joins DOC 2025 Faculty
Dr. Valter Longo, Director of the Longevity Institute at the USC-Leonard David School of Gerontology, is a leading expert in longevity and age-related diseases.
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Special Preview: This Year’s Living Room Lab
DOC 2025’s Living Room Lab features a growing list of cutting edge diagnostics available to DOC participants, including Dr. Kari Nadeau’s Microplastics Assay Kit.
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Clinical Breakthroughs | Coleen T. Murphy, Ph.D. Joins DOC 2025 Faculty
Dr. Coleen Murphy, Director of the Lewis-Sigler Institute for Integrative Genomics at Princeton, Murphy is identifying cellular mechanisms involved in the aging process.
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At DOC, We’re All Conversants
We founded DOC to reimagine what professional events can become, starting with the words we use, where everyone is a conversant.
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Longevity Research & Clinical Innovation | Eric Verdin, M.D. Appointed Senior Adviser
We are pleased to announce the appointment of Eric Verdin, M.D., CEO of the Buck Institute for Research on Aging, as DOC’s Senior Adviser.
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Clinical Breakthroughs | Max Allsworth, Ph.D. Joins DOC 2025 Faculty
As Chief Science Officer at medical research firm Owlstone Medical, Dr. Max Allsworth is deciphering details from the body’s breath to uncover diseases within.
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Women’s Health | Daisy Robinton, Ph.D. Joins DOC 2025 Faculty
Daisy Robinton, Ph.D. is singularly focused on a quest to extend ovarian health and longevity, while advocating for all women’s health.
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Longevity | Elissa Epel, Ph.D. Joins DOC 2025 Faculty
Dr. Elissa Epel, Director of UCSF’s Aging Metabolism Emotions Center, studies the intersection of well-being and stress and how they shape us as we age.
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Clinical Breakthroughs | Kari Nadeau, M.D., Ph.D. Joins DOC 2025 Faculty
As Harvard School of Public Health’s Chair of the Department of Environmental Health, Dr. Kari Nadeau investigates how changing behaviors can improve health span.
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AI & Health | Mike Krieger Joins DOC 2025
Please welcome Mike Krieger, Brazilian-born tech innovator, Instagram co-founder and Stanford graduate who has shaped how billions experience technology, to DOC 2025.
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Genomics & Longevity | Michael Snyder, Ph.D. Joins DOC 2025 Faculty
Dr. Michael Snyder, Stanford University School of Medicine’s Director of the Center of Genomics and Personalized Medicine, is a pioneer in “precision medicine.”
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Women’s Health | Britney Blair, Psy.D. Joins DOC 2025 Faculty
Dr. Britney Blair, co-founder of digital platform, Lover, focuses on educating healthcare professionals about female sexual health and is an advocate for women in business.
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Women’s Health | Jennifer Garrison, Ph.D. Joins DOC 2025 Faculty
Dr. Jennifer Garrison, Buck Institute for Research on Aging’s Co-Director of the Center for Healthy Aging in Women, studies how neuropeptide signaling contributes to aging.
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The DOCUMENT Eighth Edition
We’re shaping the DOC 2025 program, which will focus on the science of longevity and feature three thematic pillars: Clinical Breakthroughs, AI, and Women’s Health.
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DOC — Looking Back and Forward
As we turn toward DOC 2025, we’re reflecting on our core purpose: to scale high-quality, innovative science in longevity and healthcare and amplify their truths.
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DOC Seeks Exceptional CEO
We’re seeking an experienced strategic, thoughtful and entrepreneurial CEO to build DOC into an influential high-growth company that is a leader in its field.
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The DOCUMENT Seventh Edition
DOC 2025’s program, set for October 2025, will be driven by three core focus areas: AI, Longevity, and Women’s Health.
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